Search results for "community-acquired pneumonia"

showing 10 items of 51 documents

Performance of PSI, CURB-65, and SCAP scores in predicting the outcome of patients with community-acquired and healthcare-associated pneumonia

2011

The objective was to compare three score systems, pneumonia severity index (PSI), the Confusion-Urea-Respiratory Rate-Blood pressure-65 (CURB-65), and severe community-acquired pneumonia (SCAP), for prediction of the outcomes in a cohort of patients with community-acquired (CAP) and healthcare-associated pneumonia (HCAP). Large multi-center, prospective, observational study was conducted in 55 hospitals. HCAP patients were included in the high classes of CURB-65, PSI and SCAP scores have a mortality rate higher than that of CAP patients. HCAP patients included in the low class of the three severity rules have a significantly higher incidence of adverse events, including development of septi…

---medicine.medical_specialtySettore MED/09 - Medicina Internacommunity-acquired pneumoniaPneumonia severity indexBlood PressureSettore MED/10 - Malattie Dell'Apparato RespiratorioCommunity-acquired pneumonia Healthcare-associated pneumonia PSI CURB 65Severity of Illness IndexCommunity-acquired pneumoniaRespiratory RatePredictive Value of TestsInternal medicineCURB 65Severity of illnessInternal MedicinePneumonia BacterialMedicineHumansUreaPSIProspective StudiesIntensive care medicineProspective cohort studyConfusion---; community-acquired pneumonia; Healthcare-associated pneumonia; PSI; CURB 65Cross Infectioncommunity-acquired pneumonia; psi; healthcare-associated pneumonia; curb 65business.industryMortality ratemedicine.diseasePrognosisCURB-65Settore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheHealthcare-associated pneumoniaCommunity-Acquired InfectionsPneumoniaCohortEmergency Medicinebusiness
researchProduct

Smoking may increase the risk of hospitalization due to influenza.

2016

Background: Smoking may facilitate influenza virus infections and their severity. The objective was to investigate the risk of hospitalization due to influenza in Spanish smokers and ex-smokers. Methods: We carried out a multicentre, case-control study in 2011. Cases [patients a parts per thousand yen 18 years hospitalized > 24 h with real time polymerase chain reaction (RT-PCR)-confirmed influenza] were selected from 29 Spanish hospitals. For each case, we selected an outpatient aged a parts per thousand yen 18 years with RT-PCR-confirmed influenza matched by age (+/- 5 years), date of hospitalization of the case (+/- 10 days) and province of residence. We collected epidemiological variabl…

0301 basic medicineAdultMalemedicine.medical_specialtyCommunity-acquired pneumoniaAdolescentSmoking preventionCellsOrthomyxoviridaePopulationLogistic regressionExposure03 medical and health sciencesYoung Adult0302 clinical medicineRisk FactorsInternal medicineEpidemiologyInfluenza HumanmedicineOdds RatioPrevalenceCigarette-smokingResponsesHumansDisease030212 general & internal medicineYoung adultIntensive care medicineAgedAged 80 and overbiologybusiness.industrySmokingPublic Health Environmental and Occupational HealthCase-control studyOdds ratioMiddle Agedbiology.organism_classificationVaccinationHospitalization030104 developmental biologySpainCase-Control StudiesFemalebusinessInfectionEuropean journal of public health
researchProduct

Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients

2018

Abstract Background The correct management of immunocompromised patients with pneumonia is debated. We evaluated the prevalence, risk factors, and characteristics of immunocompromised patients coming from the community with pneumonia. Methods We conducted a secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia and hospitalized in 222 hospitals in 54 countries worldwide. Risk factors for immunocompromise included AIDS, aplastic anemia, asplenia, hematological cancer, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroid use, and solid tumor. Results At least 1 risk factor for immunocompromis…

0301 basic medicineMalePediatricsEtiologyMultidrug-resistant pathogenMRSAPneumocystis pneumoniaPneumònia adquirida a la comunitatHOSPITALIZED-PATIENTS0302 clinical medicineCommunity-acquired pneumoniaRisk FactorsPrevalenceMedicine030212 general & internal medicinePNEUMOCYSTIS PNEUMONIAArticles and CommentariesAged 80 and overRespiratory tract infectionsAnemia AplasticMiddle Aged3. Good healthCommunity-Acquired InfectionsEuropeInfectious DiseasesImmunocompromise; Microbiology; MRSA; Multidrug-resistant pathogens; PneumoniaEtiologiaHematologic NeoplasmsFemaleBLOOD-STREAM INFECTIONSLung TransplantationMicrobiology (medical)medicine.medical_specialtyAsiaNeutropeniaCommunity-acquired pneumonia030106 microbiologyRESPIRATORY-TRACT INFECTIONSHematologic NeoplasmsSettore MED/10 - Malattie Dell'Apparato RespiratorioTRANSPLANT RECIPIENTSDISEASES-SOCIETYMicrobiology03 medical and health sciencesImmunocompromised HostPneumonia BacterialMANAGEMENTHumanspneumoniaBACTERIAL PNEUMONIAImmunocompromiseAgedAcquired Immunodeficiency Syndromebusiness.industrymicrobiologyBacterial pneumoniaAustraliaPneumoniamedicine.diseaseMultidrug-resistant pathogensPneumoniamultidrug-resistant pathogensMycosesBacteremiaAfricaEtiologyRISK-FACTORSimmunocompromiseAmericasbusinessClinical Infectious Diseases
researchProduct

International prevalence and risk factors evaluation for drug-resistant Streptococcus pneumoniae pneumonia

2019

Objective: Streptococcus pneumoniae is the most frequent bacterial pathogen isolated in subjects with Community-acquired pneumonia (CAP) worldwide. Limited data are available regarding the current global burden and risk factors associated with drug-resistant Streptococcus pneumoniae (DRSP) in CAP subjects. We assessed the multinational prevalence and risk factors for DRSP-CAP in a multinational point-prevalence study. Design: The prevalence of DRSP-CAP was assessed by identification of DRSP in blood or respiratory samples among adults hospitalized with CAP in 54 countries. Prevalence and risk factors were compared among subjects that had microbiological testing and antibiotic susceptibility…

0301 basic medicineMaleStreptococcus pneumoniaantibiotic resistanceInternationalitysputum examinationbronchiectasisvery elderlyAntibioticsPrevalenceDrug resistancemedicine.disease_causeLogistic regressionGlobal HealthCommunity-Acquired Infections/epidemiologylung lavage0302 clinical medicineCommunity-acquired pneumoniaCost of IllnessRisk FactorsPrevalencedrug resistant Streptococcus pneumoniae pneumonia030212 general & internal medicineMicrobial drug resistantAged 80 and overadultinternational cooperationdrug effectMiddle Agedinfluenza vaccinationAnti-Bacterial Agentsantiinfective agentEuropeCommunity-Acquired InfectionsHospitalizationGlobal burden of diseaseStreptococcus pneumoniaeInfectious Diseasesrisk factorbacterium identificationFemalecommunity acquired infectioninfluenzaliver diseasepneumococcal vaccinationPneumococcal infectionhospitalizationmedicine.drugMicrobiology (medical)medicine.medical_specialtyAsiamedicine.drug_class030106 microbiologySettore MED/10 - Malattie Dell'Apparato RespiratorioArticleAnti-Bacterial Agents/pharmacology03 medical and health sciencesInternal medicineStreptococcus pneumoniaeDrug Resistance BacterialPneumonia Pneumococcal/epidemiologymedicineHumanscontrolled studyhumantetracyclineHospitalization/statistics & numerical dataAgedlevofloxacinnonhumanbusiness.industrydisease associationmicrobiologycommunity acquired pneumoniamacrolidePneumoniaasthmaSouth AmericaPneumonia Pneumococcalvaccinationmedicine.diseasemajor clinical studyantibiotic sensitivitypenicillin derivativePenicillinStreptococcus pneumoniae/drug effectsPneumoniablood examinationAfricaNorth Americamicrobiological examinationbusinessGlobal burden of disease; Microbial drug resistant; Pneumococcal infection; Pneumonia
researchProduct

Multidimensional Prognostic Index and pro-adrenomedullin plasma levels as mortality risk predictors in older patients hospitalized with community-acq…

2018

BACKGROUND: To evaluate the prognostic accuracy of proadrenomedullin (proADM) in comparison with and in addition to the Multidimensional Prognostic Index (MPI), a validated predictive tool for mortality derived from a comprehensive geriatric assessment (CGA) to predict one-month mortality risk in older patients hospitalized with community-acquired pneumonia (CAP). METHODS: All patients aged 65 years and older, consecutively admitted to an acute geriatric ward with a diagnosis of CAP from February to July 2012. At admission and at discharge they were submitted to a standard CGA in order to calculate MPI. Moreover, plasma samples were taken at baseline and after one, three and five days of ho…

0301 basic medicineMalemedicine.medical_specialtySeverity of Illness Index03 medical and health sciencesAdrenomedullin0302 clinical medicinePatient AdmissionOlder patientsCommunity-acquired pneumoniaPredictive Value of TestsRisk FactorsInternal medicineSeverity of illnessRisk of mortalityMedicineHumansProspective StudiesProtein PrecursorsProspective cohort studyGeriatric AssessmentAgedProportional Hazards ModelsAged 80 and overbusiness.industryProportional hazards modelGeneral MedicinePneumoniamedicine.diseasePrognosisPatient DischargeCommunity-Acquired InfectionsPneumonia030104 developmental biology030220 oncology & carcinogenesisPredictive value of testsFemalebusinessPanminerva medica
researchProduct

Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study

2018

This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary anti…

0301 basic medicinePulmonary and Respiratory Medicinemedicine.medical_specialtycommunity-acquired pneumoniaCommunity-acquired pneumoniaPatients4Concordance030106 microbiologyRespiratory Systemlcsh:MedicineSettore MED/10 - Malattie Dell'Apparato RespiratorioGUIDELINESPneumònia adquirida a la comunitatSputum cultureSerology03 medical and health sciences0302 clinical medicineCommunity-acquired pneumoniaInternal medicinemedicineMANAGEMENTBlood culture030212 general & internal medicinePOPULATIONpneumonia Methicillin-resistant Staphylococcus aureus PneumoniaScience & Technologymedicine.diagnostic_testbusiness.industryMORTALITYlcsh:RMicrobiologia mèdicaOriginal ArticlesGuidelinePneumoniaMedical microbiologymedicine.diseaseMicrobiologicalETIOLOGYPneumoniaDiagnostic testingREQUIRING HOSPITALIZATIONbusinessLife Sciences & BiomedicineCohort studyERJ Open Research
researchProduct

Comparison of clinical characteristics between coronavirus disease 2019 pneumonia and community-acquired pneumonia

2020

Coronavirus disease 2019 (COVID-19) has high morbidity and mortality, and spreads rapidly in the community to result in a large number of infection cases. This study aimed to compare clinical features in adult patients with coronavirus disease 2019 (COVID-19) pneumonia to those in adult patients with community-acquired pneumonia (CAP).Clinical presentations, laboratory findings, imaging features, complications, treatment and outcomes were compared between patients with COVID-19 pneumonia and patients with CAP. The study group of patients with COVID-19 pneumonia consisted of 120 patients. One hundred and thirty-four patients with CAP were enrolled for comparison.Patients with COVID-19 pneumo…

AdultMaleChinamedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Pneumonia Viral030204 cardiovascular system & hematologySeverity of Illness IndexBetacoronavirus03 medical and health sciences0302 clinical medicineCommunity-acquired pneumoniaInternal medicineSeverity of illnessPandemicmedicineHumans030212 general & internal medicinePandemicsAgedRetrospective StudiesbiologySARS-CoV-2business.industryCase-control studyCOVID-19Retrospective cohort studyGeneral MedicineMiddle AgedPrognosisbiology.organism_classificationmedicine.diseaseCommunity-Acquired InfectionsPneumoniaCase-Control StudiesFemaleCoronavirus InfectionsbusinessBetacoronavirusCurrent Medical Research and Opinion
researchProduct

Assessment of Analysis of Urinary Pneumococcal Antigen by Immunochromatography for Etiologic Diagnosis of Community-Acquired Pneumonia in Adults

2006

ABSTRACT The limitations of conventional microbiologic methods (CMM) for etiologic diagnosis of community pneumococcal pneumonia have made faster diagnostic techniques necessary. Our aim was to evaluate the usefulness of the immunochromatography (ICT) technique for detecting urinary Streptococcus pneumoniae antigen in the etiologic diagnosis of community-acquired pneumonias (CAP). This was a prospective study on in-patients with CAP in a tertiary hospital conducted from October 2000 to March 2004. Apart from using CMM to reach an etiologic diagnosis, we determined pneumococcal antigen in concentrated urine by ICT. We also determined the urinary pneumococcal antigen (UPA) content in patients…

AdultMaleMicrobiology (medical)medicine.medical_specialtyAdolescentClinical BiochemistryImmunologymedicine.disease_causeCommunity-acquired pneumoniaInternal medicineStreptococcus pneumoniaemedicineHumansImmunology and AllergyProspective StudiesAgedAged 80 and overAntigens BacterialChromatographyCOPDbusiness.industryClinical and Diagnostic Laboratory ImmunologyRespiratory infectionMiddle AgedPneumonia Pneumococcalmedicine.diseaseCommunity-Acquired InfectionsPneumoniaPneumococcal infectionsStreptococcus pneumoniaePneumococcal pneumoniaImmunologyImmunologic TechniquesEtiologyFemalebusinessClinical and Vaccine Immunology
researchProduct

Can CAP guideline adherence improve patient outcome in internal medicine departments?

2008

The impact of compliance with Italian guidelines on the outcome of hospitallised community-acquired pneumonia (CAP) in internal medicine departments was evaluated. All Fine class IV or V CAP patients were included in this multicentre, interventional, before-and-after study, composed of three phases: 1) a retrospective phase (RP; 1,443 patients); 2) a guideline implementation phase; and 3) a prospective phase (PP; 1,404 patients). Antibiotic prescription according to the guidelines increased significantly in the PP. The risk of failure at the end of the firstline therapy was significantly lower in the PP versus the RP (odds ratio (OR) 0.83, 95% confidence interval (CI) 0.69-1.00), particular…

AdultMalePulmonary and Respiratory MedicinePediatricsmedicine.medical_specialtycommunity acquired-pneumonia guideline internal medicineadherenceCritical Caremedicine.drug_classAntibioticsPopulationCommunity-acquired pneumoniaLevofloxacinInternal medicineInternal MedicinemedicineHumansProspective StudieseducationAgedRetrospective StudiesAged 80 and overeducation.field_of_studybusiness.industryPneumoniaOdds ratioGuidelineMiddle Agedmedicine.diseaseConfidence intervalCommunity-Acquired InfectionsPneumoniaTreatment OutcomeItalyFemaleGuideline Adherencebusinessmedicine.drugEuropean Respiratory Journal
researchProduct

Is it possible to predict which patients with mild pneumonias will develop hypoxemia?

2009

SummaryUsually, mortality due to mild community-acquired pneumonias (CAP) (Pneumonia severity index (PSI) classes I–III) is low (<3%), but the appearance of hypoxemia significantly increases mortality. Our aim was to determine the clinical parameters associated with risk factors of developing hypoxemia in subjects with mild CAP (PSI I–III) and the clinical outcomes of the hypoxemic group.We analyzed clinical characteristics and the outcomes of patients with mild CAP and hypoxemia (PaO2/FiO2<300), in a prospective, multicenter cohort study of 1195 patients.Mild pneumonias (PSI I–III) were found in 645 cases (53.9%), of which 217 (33.6%) presented hypoxemia according to a PaO2/FiO2<300. Patie…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyAdolescentCommunity-acquired pneumoniamedicine.medical_treatmentPneumonia severity indexSeverity assessmentHypoxemiaHypoxemiaPulmonary Disease Chronic ObstructiveYoung AdultCommunity-acquired pneumoniaHumansMedicineHypoalbuminemiaHypoxiaAgedMechanical ventilationCOPDbusiness.industrySeptic shockPneumoniaMiddle Agedmedicine.diseaserespiratory tract diseasesSurgeryCommunity-Acquired InfectionsRadiographyPneumoniaRisk factorsAnesthesiaFemalemedicine.symptomEpidemiologic MethodsbusinessHypoalbuminemiacirculatory and respiratory physiologyRespiratory Medicine
researchProduct